Brief Analysis of Insecticide Carbosulfan
What is carbosulfan?The insecticide carbosulfan is an organic compound belonging to carbamates with the molecular formula C20H32N2O3S and Cas 55285-14-8. The pure product is a colorless or pale yellow oily liquid with a vapor pressure of 4.1×104 Pa at room temperature. Insoluble in water, easily soluble in organic solvents.
One of the low-toxic varieties of insecticide carbofuran, with moderate oral toxicity, low skin toxicity, no cumulative toxicity, no deformity, carcinogenicity and mutagenicity. It has low toxicity to natural enemies and beneficial organisms, that is, the low-toxicity derivative of carbofuran pesticide, which is an efficient, safe, and easy-to-use insecticide and acaricide, and is one of the ideal substitutes for the highly toxic pesticide carbofuran. It has strong lethality, quick effect, and has stomach poisoning and contact killing effects.
The toxicity mechanism of the insecticide carbofuran is to inhibit the activity of insect acetylcholine (Ach) and carboxylesterase, resulting in the accumulation of acetylcholine (Ach) and carboxylate, affecting the normal nerve conduction of insects and causing death. It is characterized by fat solubility, good systemic absorption, strong penetration, rapid action, low residue, long residual effect, safe use, etc. It is effective for both adults and larvae, and is harmless to crops. It can control various economic crop pests such as citrus and other fruits and vegetables, corn, cotton, rice, sugarcane, etc., and the control effect on aphids is particularly excellent.
The insecticide carbosulfan belongs to carbamates, and its toxicity mechanism is to inhibit the activity of insect 7-acylcholinease (Ache) and carboxylic acid complexing enzymes, resulting in the accumulation of acetylcholine (Ach) and carboxylic acid esters, affecting insects Normal nerve conduction is fatal.
Carbosulfan (55285-14-8) preparation
20% Carbosulfan (Hao Nian Dong) EC; 5% Carbosulfan Granules.
Active ingredient content ≥ 5.0%; moisture content ≤ 5.0%; shedding rate ≤ 5.0%. The application concentration is 5mg/L, and the dosage is 6.8-15g/100m2 (active ingredient).
Carbosulfan (55285-14-8) preparation method
method one
1. Preparation of di-n-butylaminosulfur chloride: Add di-n-butylamine and petroleum ether (60-90°C), stir and cool to 0°C, then slowly add trisulfur dichloride dropwise, maintain 0-10°C, and finish adding After incubation for 2 hours, the ratio of di-n-butylamine, disulfur dichloride and sulfuryl chloride was 1:0.6:0.55 (mol), and the yield was 88%.
2. Synthesis of carbofuran (55285-14-8): Di-n-butylaminosulfur chloride reacts with carbofuran at a ratio of 1:1, adding appropriate amount of lye during the reaction, and the reaction temperature is 10-20°C. Reaction time 2h. After the reaction, add water and stir for 10 minutes, filter, and the filter residue is unreacted carbofuran, which can be reused. The filtrate was separated, and the oil layer was precipitated under reduced pressure, with a yield of 90%.
Method Two:
Starting from cyclohexanone and isobutyraldehyde, it is synthesized through five steps of aldol condensation, chlorination reaction, aromatic ring reaction, hydrolysis reaction and ring closure reaction. It is characterized by the synthesis of non-aromatic compounds and is a highly selective synthetic route.
Carbosulfan (55285-14-8) physical and chemical properties
The original drug contains 92.0% carbosulfan. The appearance is a viscous brown liquid with a specific gravity of 1.065-1.082, a boiling point of 124-128°C, a flash point of 115-117°C, and a vapor pressure (25°C) of 41.3×10-6Pa. The solubility in water is 0.3 mg/L. The solubility in xylene, hexane, chloroform, dichloromethane and methanol is 50%. Under aerobic and anaerobic conditions, it decomposes quickly in the soil, and the half-life in the laboratory is less than 5 days. It decomposes quickly in water, and is hydrolyzed into carbofuran very quickly under acidic conditions. Under the fluorescent lamp, the half-life of 5 micrograms/ml Carbosulfan in pH7 buffer solution is 1.4 days, and 4-8 days in distilled water. It cannot burn, but it can support combustion and is stable under neutral and slightly alkaline conditions.
The appearance of 20% Haoniandong EC is light brown viscous liquid with a specific gravity of 0.923 (20°C). The preparation is diluted 1-100 times with 50-100 mg/L hard water, and the emulsion has good stability. Compatible with most pesticides and fertilizers. It has good stability when stored at 50°C for 6 months or at room temperature for more than 1 year.
The appearance of 35% Haoniandong seed treatment agent is red powder, and the active ingredient content is 350 g/kg. It can be mixed with other fungicides for seed treatment.
Carbosulfan (55285-14-8) Toxicity
The insecticide carbofuran is a moderately toxic insecticide and acaricide.
Original drug: the acute oral LD50 of rats is 209 mg/kg.
Welling EC: The acute oral LD50 for rats is 115 mg/kg.
Application of Carbosulfan (55285-14-8)
Insecticide carbosulfan is a carbamate insecticide, suitable for citrus, rice, vegetables, apples, pear trees, etc., and is often used to control aphids, leaf miners, thrips, rice gall Mosquitoes and underground pests.
The insecticide carbofuran is characterized by fat solubility, good systemic absorption, strong penetration, rapid action, low residue, long residual effect, safe use, etc. It is effective against adults and larvae, and is harmless to crops.
The pesticide carbofuran is suitable for citrus, rice, corn, cotton, sugarcane, vegetables, apples, pear trees, etc. It is often used to control aphids, leaf miners, thrips, rice gall midges and underground pests. The control effect is particularly excellent.
Carbosulfan (55285-14-8) effect
The insecticide carbofuran is a low-toxic derivative of the pesticide, which is an efficient, safe, and easy-to-use insecticide and acaricide, and is one of the ideal substitutes for the highly toxic pesticide carbofuran. It has strong lethality, quick effect, and has stomach poisoning and contact killing effects. It is characterized by fat solubility, good systemic absorption, strong penetration, rapid action, low residue, long residual effect, safe use, etc. It is effective for both adults and larvae, and is harmless to crops.
1. It is used for the control of more than ten kinds of pests such as rust ticks, aphids, thrips, and leafhoppers on fruit trees, cotton, vegetables, grains, and other economic crops.
2. It is a low-toxic insecticide with systemic and broad-spectrum properties
3. High systemic and broad-spectrum carbamate insecticides, acaricides and nematicides. It is a low-toxic carbofuran variety, which is used to control aphids, mites, needleworms, beet worms, potato beetles, tea leafhoppers, pear borer worms, apple leaf rollers, etc. in citrus, fruit trees, cotton, and rice crops. pests. The application concentration is 5mg/L, and the dosage is 6.8-15g active ingredient/100m2.
4. The insecticide carbofuran is a derivative of carbofuran, which has comparable insecticidal activity to carbofuran, but its toxicity is much lower than that of carbofuran. It is a gastric toxic insecticide and is metabolized into furan in the organism The dan then exerts its medicinal effect to kill the insects. It has a good control effect on pests such as potato green peach aphid, black light beetle, highly dyed blind horn fly, cutworm and so on. In addition, it also has good control of cotton spider mite, grain elephant, miscellaneous corn beetle, and Trichosporum moth.
Uses of Carbosulfan (55285-14-8)
The Insecticide carbofuran is used to control more than ten kinds of pests such as rust ticks, aphids, thrips and leafhoppers on fruit trees, cotton, vegetables, grains and other economic crops. Carbosulfan is a highly systemic and broad-spectrum carbamate insecticide, acaricide, and nematicide. Carbosulfan can be used for citrus, fruit trees, cotton, rice crops such as aphids, mites, wireworms, sugar beet beetle beetle, potato beetle, pear borer, tea leafhopper, apple leaf tortrix and other pests. In addition, it also has good control of cotton spider mite, grain elephant, miscellaneous corn beetle, and Trichosporum moth.
The insecticide carbosulfan is a derivative of carbofuran, which has comparable insecticidal activity to carbofuran, but its toxicity is much lower than that of carbofuran. It is a gastric toxic insecticide and is metabolized into furan in the organism The dan then exerts its medicinal effect to kill the insects. It has a good control effect on pests such as potato green peach aphid, black light beetle, highly dyed blind horn fly, cutworm and so on.
The insecticide carbofuran is a highly systemic and broad-spectrum carbamate insecticide, acaricide, and nematocide. It is a low-toxic carbofuran variety, which is used to control aphids, mites, needleworms, beet worms, potato beetles, tea leafhoppers, pear small borers, apple leaf rollers, etc. in citrus, fruit trees, cotton, and rice crops. pests. The application concentration is 5mg/L, and the dosage is 6.8-15g active ingredient/100m2.
Carbosulfan is a derivative of carbofuran, which has comparable insecticidal activity to carbofuran, but its toxicity is much lower than that of carbofuran. Its medicinal effect kills insects. It has a good control effect on pests such as potato green peach aphid, black light beetle, highly dyed blind horn fly, cutworm and so on. In addition, it also has good control of cotton spider mite, grain elephant, miscellaneous corn beetle, and Trichosporum moth.
How to use Carbosulfan (55285-14-8)
First of all, when using carbosulfur Budweiser, it should be noted that the maximum number of times of use per season and the interval between safety periods are different for different crops, cabbage 2 times, 7 days; citrus 2 times, 15 days; apple 3 times, 30 days; zucchini 2 times, 7 days; cotton 2 times, 30 days; rice 1 time, 30 days. And what needs to be paid attention to when using carbosulfan is that it cannot be directly sprayed in ponds, lakes, rivers and other water bodies or swamp wetlands. Agents blown by wind or washed away by rain from the application area may pose a hazard to nearby aquatic life. Do not wash utensils or dispose of remaining chemicals in the water source, so as not to cause water pollution.
1. Vegetable pests. For the prevention and control of cabbage butterfly, the suitable period for the control of the first generation should be about 1 week after the peak of spawning, that is, before the vegetable is in the core stage, apply 20% EC 3L/hm2 (active ingredient 600g/hm), use a backpack machine Spray on water. To control blue aphids, use 20% Carbosulfan EC at 3kg/hm2 (containing 600g/hm2 of active ingredients) and spray it on water.
2. Rice brown planthopper. At the end of rice booting or round stem stage, at the booting stage or heading stage, at the milky or waxy stage of filling milk, use 2.25L/hm2 of 20% carbosulfan EC (containing 450g/hm2 of active ingredients) to water 750kg spray.
3. Control citrus rust mite. Good year and winter can effectively control various pests of citrus, among which the effect of controlling orange rust mite (commonly known as rust tick) is particularly outstanding, and the effective period can generally be maintained at 40-60 days or more. Because the peak period of citrus rust mite is the autumn shoot, and citrus aphids and leaf miners also occur at the same time, the 20% EC with a dilution factor of 2000 to 3000 times can control the above pests.
①. Control citrus rust spiders. Spray at the initial stage of rust spider occurrence when the new shoots are 1 cm long, spray with 20% Haoniandong EC 1500-2000 times (effective concentration 100-133.3mg/kg), spray once every 5 days, 2-3 times in a row. The anti-spider effect is remarkable, and the validity period is more than 40 days.
②. Control citrus leafminer. Spray at the early release of new shoots or the hatching period of leafminer eggs, spray with 20% Haoniandong EC 1000-1500 times (effective concentration 133.3-200mg/kg), while effectively controlling leafminer, it can At the same time, it can prevent rust spiders, aphids and psyllids, etc., thereby reducing the frequency of pesticide use. This product is a good replacement product for other agents for preventing and controlling leaf miners, such as permethrin, dimethoate emulsion and dimehypo.
③. Control orange aphid. Aphids are the main pests in the spring shoot stage, citrus full bloom to young fruit stage. Applying pesticides during the occurrence of aphids, spraying with 1000-1500 times of 20% Haoniandong EC (effective concentration 133.3-200mg/kg) can effectively eliminate aphids and reduce the number of rust spiders.
④. Control rice thrips. Soak the seeds in the conventional way, dress the seeds with 35% Haoniandong seed treatment agent after germination, and then sow the seeds in tatani. Seed-dressing treatment in good year and winter can effectively control the damage of rice thrips in the late rice seedling stage.
⑤. Control rice flaccid mosquito. After soaking and accelerating germination by conventional methods, use 35% Haoniandong seed treatment agent for seed dressing, and the dosage is 1.7% to 2.28% of the dry seed weight (0.6% to 0.8% of the active ingredient).
4. For the prevention and control of rice planthoppers: use 150ml of 20% carbosulfan EC per mu of rice, mix with 30-50kg of water and spray evenly on the rice.
5. Used to prevent and control citrus rust spiders: when the citrus shoots grow to 1 cm and the rust spiders occur in the early stage, use 50-70 ml of 20% carbosulfan emulsifiable concentrate per mu of citrus orchards, and mix with 100 kg of water to evenly spray the fruit trees .
6. For the prevention and control of citrus leafminer: in the early stage of citrus shoots or the peak hatching stage of leafminer eggs, use 70-100ml of 20% carbosulfan EC per mu, mix 100kg of water, and spray evenly on the fruit trees. It can also control pests such as spiders, aphids and psyllids.
7. Used to prevent and control apple aphids and tumor aphids: During the vigorous growth period of new shoots of apples, use 50-70 ml of 20% carbosulfan EC per mu of orchard, and mix with 100 kg of water to spray evenly on the fruit trees. This spraying can It also treats the golden moth.
8. For the control of rice stem borer: Spray 1-2 days before the hatching peak of rice stem borer, and spray evenly with 200-250 ml of 20% carbosulfan EC mixed with water per mu of rice.
What is the difference between carbofuran and carbosulfan? Which pests can be used to control?
The two are a pair of very similar carbamate insecticides, which have contact killing, stomach poisoning and systemic effects, and can be used to control various crop pests. However, the toxicity of carbofuran is higher than that of carbosulfan, which is highly toxic to humans and animals, while carbosulfan is moderately toxic to humans and animals, and is relatively safe to natural enemies, beneficial organisms and pesticide applicators. Carbosulfan is mainly used as foliar spray, while carbofuran cannot be used for spraying, and can only be made into granules for spreading or burying in the soil.
(1) Control rice pests: control rice stem borer, rice stem borer, rice planthopper, rice thrips, rice gall midge and other pests, use 2-3 kg of 3% granules per mu before sowing and inserting Dry sand is applied to the root zone, and the residual effect period is 40-50 days; the application of pesticides before sowing in the seedbed has special effects on the control of rice gall midges on seedlings. It can also be applied on the water surface after insertion, and the application should be even and keep a certain shallow water layer. Due to the high toxicity of carbofuran and long residual effect period, care should be taken when using rice field water not to pollute fish ponds, rivers, and lakes, and the application should be stopped 2 months before rice harvest.
(2) Control cotton pests: control cotton seedling aphids, cutworms, and thrips, apply them in the ditch when sowing, or dig holes on the root side after sowing, and topdress the pesticide in the soil for 5-10 days cm, and then covered with soil, using 1.5-2 kg of 3% carbofuran granules per mu. In order to spread the medicine evenly, mix it with dry sand and apply the medicine.
(3) Control sugarcane pests: control sugarcane borers, cotton aphids, needleworms and sugarcane nematodes, etc., apply pesticides in the sowing ditch, and then cover the soil synchronously with the sowing, and use 3-5 kg of 3% carbofuran granules per mu.
(4) Prevention and control of peanut pests: control peanut root-knot nematodes and aphids, apply soil pesticides simultaneously with peanut sowing, or apply pesticides on the side of the row after the peanuts grow into plants, and then cover with soil, using 3% carbofuran per mu Granules 4-5 kg.
(5) Control of citrus pests: To control citrus miner, apply pesticides at the 2-3 leaf stage of new shoots, and at the peak of egg hatching, and control citrus aphids when the rate of aphids on new shoots reaches 10%, preferably 20% Spray evenly with 1000-1500 times liquid of Niandong EC; to control citrus rust tick, spray evenly with 1500-2000 times liquid of 20% Haoniandong EC during the peak occurrence period. At the same time, it can also control psyllids, scale insects, etc., and also has a certain inhibitory effect on red spiders.
(6) Prevention and control of apple pests: To control apple yellow aphid, spray evenly with 20% Haoniandong EC 3000-4000 times during the peak occurrence period. At the same time, it can also control pests such as aphids and borers.
(7) Prevention and control of vegetable pests: to control cabbage aphids, spray evenly with 20% Haoniandong EC 1500-2500 times during the occurrence period; Milliliter spray evenly on water.
The role of carbofuran
Carbofuran is a carbamate broad-spectrum systemic insecticide and nematicide with contact and stomach toxicity. Its toxicological mechanism is to inhibit cholinesterase, but unlike other carbamate insecticides, its combination with cholinesterase is irreversible, so its toxicity is high.
How to use Carbofuran
1. Control of rice pests To control rice borers, rice planthoppers, rice thrips, rice leafhoppers, rice gall midges, etc., the following methods can be used:
(1) Applying pesticides in the root zone, before sowing or transplanting, use 2.5-3kg of 3% granules per mu.
(2) For water surface application, use 1.5-2kg of 3% granules per mu, mix with 15-20kg of fine soil, and spread evenly on the water surface.
(3) Applying pesticides in the seeding ditch. In the upland rice planting area, 3% granules are simultaneously applied in the seeding ditch, and the dosage per mu is 2.0-2.5kg.
2. Control of cotton pests To control cotton aphids, thrips, cutworms and nematodes, the following methods can be selected according to local conditions.
(1) Apply pesticides in the sowing ditch, use 1.5-2kg of 3% granules per mu.
(2) Topdressing on the root side, using 2-3kg of 3% granules per mu in furrow application, 10-15cm away from the cotton plant, and the depth is 5-10cm. It is advisable to apply 0.5-1g of 3% granules per hole.
(3) For seed treatment, the dosage is 1/4 of the dry seed weight.
3. Control of tobacco pests Carbofuran is effective against tobacco armyworm, tobacco aphid, tobacco root-knot nematode and tobacco leaf miner, and can control pests such as cutworms and mole crickets.
(1) For seedbed application, use 15-30g of 3% granules per square meter.
(2) For Honda application, apply 1-1.5g of 3% carbofuran granule in the transplanting hole.
4. Prevention and control of sugarcane pests Carbofuran is effective against sugarcane borers, wireworms, sugarcane thrips, sugarcane nematodes, etc., and can be applied in the soil. Use 2.2-4.4kg of 3% granules per mu and cover with soil after application.
5. Prevention and control of soybean pests For the control of soybean and flower insect pests, use 4-5kg of 3% granules per mu, and cover with soil after application.
Precautions for use of carbofuran
1. Carbofuran is highly toxic. Be careful when using it. Spraying Carbofuran is strictly prohibited.
2. Carbofuran should not be used in combination with propanil and fenzamid in rice fields to avoid phytotoxicity.
3. The drug is atropine, and the use of pralidoxime is strictly prohibited.
4. Vegetables, fruit trees, tea and other crops that are directly edible are prohibited.
Precautions for Carbosulfan (55285-14-8)
1. The insecticide carbosulfan has poor control effect on rice stem borer and rice leaf roller, so it should not be used.
2. When spraying pesticides in rice fields, do not apply propanil and fenzamid to prevent phytotoxicity.
3. In case of accidental poisoning, make the patient breathe fresh air. If the eyes come into contact with the agent, rinse immediately with water. In case of poisoning, do not use oxime drugs during treatment, but inject atropine intramuscularly first. If swallowed by mistake, do not induce vomiting and ask a doctor for treatment. Inject 2ml of atropine for detoxification, but do not use oxime antidote, such as 2-DAM; if inhaled poisoning, immediately move the patient to a place with fresh air, and ask a doctor for diagnosis and treatment. If the liquid splashes into the eyes, rinse with water for at least 15 minutes, and consult a doctor. If skin gets contaminated with liquid medicine, remove contaminated clothing and flush with plenty of water.
4. The safe interval on vegetables is 25 days, so it is strictly forbidden to use the medicine 25 days before harvest.
Mixture of carbosulfan and other medicines
The seed treatment formulation can be mixed with other fungicides for seed treatment.
Carbosulfan Budweiser needs to pay attention to the use of carbosulfan Budweiser, do not mix it with alkaline pesticides and other substances, and do not contact with seeds. And the most important point is that when using carbosulfan, you should tidy yourself up first, and wear protective clothing and gloves. Be sure to refrain from eating, drinking or smoking during the application of the medicine. Remember to wash your hands and face in time after applying the medicine.
Carbosulfan (55285-14-8) degradation metabolism
The metabolic principle of the insecticide carbosulfan is similar to that of carbofuran. In animals, it is transformed into phenols with low toxicity, and most of the metabolites are excreted in urine. It is transformed into carbofuran and highly active 3-hydroxy carbofuran in insects and plants, and further is the hydrolysis, oxidation and combination of carbofuran. It degrades rapidly in soil with a half-life of 2 to 3 days.
Carbosulfan (55285-14-8) allowable residue
The maximum allowable residue: human ADI value 0.01mg/kg. body weight, 0.2mg/kg for rice, 1mg/kg for potatoes, 5mg/kg for strawberries, 0.2mg/kg for fruits, 1mg/kg for vegetables, 0.2mg for sugar cane /kg.
The price of the insecticide carbosulfan (55285-14-8)
Usually, the price of the pesticide carbosulfan will be affected by raw materials, market environment, research and development costs, etc. If you want to know the latest price of the pesticide carbosulfan you need, please contact us to initiate an inquiry.
Tel: 13563082345 Email: sales@agripesticide.com
Supplier of the insecticide Carbosulfan (55285-14-8)
Agripestcide is a professional agrochemical manufacturer, providing herbicides, insecticides, microbial fungicides, plant growth regulators and other products. If you are looking for Pesticide Insecticide Carbosulfan, please feel free to contact us for latest price.