Herbicide Products - Mefenacet Application
What is herbicide Mefenacet?Mefenacet is a member of benzothiazoles and a tertiary carboxamide. It has a role as an antimitotic and a herbicide.Cas 73250-68-7Mefenacet is a herbicide used for pre- and early post-emergence control of weeds including annual gramineae weeds and leptochloa chinensis, eleocharis acicularis, wartwort, monochoria vaginalis, rotala indica and perennial aquatic cyperus rotundus mainly in rice crops.
mefenacet belongs to the phthaloanilide chemical herbicides, mainly used in transplanted rice fields, is an inhibitor of grass weed cell growth and division, can effectively control grass weeds, has special effects on barnyard grass, and is effective on rice fields It is also effective in controlling annual weeds, cattle felt, melon skin grass, Alisma, etc., and has excellent selectivity for transplanting rice fields. Rice is a key crop for development in my country. In order to ensure the high yield of rice and increase its yield per unit area, the use of excellent chemical herbicides is a crucial means.
Mode of action and mechanism of mefenacet
Mefenacet is an anilide herbicide, which is an inhibitor of cell growth and division. It has a particularly strong inhibitory effect on the division of mother cells. It has been observed that the drug works at the growth point of the plant in the quiescent phase and the metabolic phase of the cell reproduction cycle, and inhibits cell division and enlargement, thereby hindering the growth of barnyardgrass until death. The appearance symptoms of barnyardgrass treated with the drug are: the growth points of the stems, leaves and roots are abnormally hypertrophied, the leaf sheaths turn dark green, the growth of the plants is inhibited, and eventually the stems and leaves turn yellow and die.The withering time of barnyardgrass prolongs with the increase of leaf age.
How to use herbicide Mefenacet
In the transplanted paddy field, the pesticide is applied 3 to 10 days after transplanting (at the 2-leaf stage of barnyard grass) and 3 to 14 days (at the 3-leaf or 3.5-leaf stage of barnyardgrass). Dosage: 4% mefenacet granule 2-2.7 kg/mu. The effective dosage of barnyardgrass depends on the leaf age: 1.5 leaves, 2.5 leaves, 3.5 leaves, and 4 leaves are 33 grams, 67 grams, 100 grams, and 133 grams per mu of active ingredients. The maintenance time of the drug effect in the paddy field varies with the dosage: 30 days for 67 grams of active ingredient, 50 days for 100 grams, and 60 days for 133 grams. mefenacet the solubility of this agent in water is only 4mg/l, and the soil has strong adsorption capacity and less penetration. Under normal paddy field conditions, most of the application amount is distributed within 1cm of the surface layer, forming a treatment layer. The growth of seedlings should not be in contact with this layer. mefenacet has excellent selectivity to transplanted rice. 50% mefenacet EC can also be used to control weeds in dry fields, and 8 kg per hectare can be used as pre-emergence soil surface treatment for weeds. Chickweed has good control effect.
Herbicide Mefenacet Usage
Selective, inhibits cell division and growth. Inhibition of VLCFA (inhibition of cell division).
Selective systemic herbicide, inhibitor of cell growth and division. Absorbed by colephyllum and root, accumulating at the growth point to stop weeds’ growth. Control of annual weeds on transplanting rice field in cold area: 450~600g a.i./ha. In tropical and subtropical area: 375~450g a.i./ha. Specific dosage depends on different situation.
Mefenacet Used pre-emergence and early post-emergence, mainly in transplanted rice, to control grass weeds (with a specific action against Echinochloa crus-galli). Preferably used in mixtures with other herbicides.
Mefenacet Selective pre- and post-emergence control of annual and perennial weeds and sedges (e.g. Butomus umbellatus, Scirpus maritimus, Scirpus mucronatus, Alisma plantago-aquatica, Sparganium erectum, Cyperus , Typha , etc.) in continuously flooded rice.
Mefenacet Control of annual grasses and some broad-leaved weeds in maize, sorghum, cotton, sugar beet, fodder beet, sugar cane, potatoes, peanuts, soya beans, safflowers, sunflowers, various vegetables, fruit and nut trees, and woody ornamentals. Applied pre-emergence, pre-plant incorporated or early post-emergence. Often used in combination with broad-leaved herbicides, to extend the spectrum of activity.
Applications of herbicide Mefenacet
mefenacet is Cytogenesis and division inhibitor, low toxicity. It is mainly used to control gramineous weeds. It is a highly active barnicide in paddy fields and can kill barnyard grass before it occurs to the three-leaf stage. Effective against annual weeds and fescue. It has good selectivity for transplanting rice, has quick effect from before emergence to early emergence, and lasts for more than 30 days. The method of application can be sprinkled with water. It is mainly used in transplanting fields and seedling throwing fields, and can effectively control grass weeds.
Herbicide Mefenacet price
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Herbicide Mefenacet supplier
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What is the function herbicide Mefenacet
Mefenacet (2-(2-benzothiazolyl-oxy)-N-methyl-N-phenylacetamide) (Fedtke, 1987) works as a very long chain fatty acid (VLCFAs) synthesis inhibitor of the HRAC Group 15, α-oxyacetamides subgroup. Mefenacet has been commercialized for more than six decades. With low toxicity and high efficacy, mefenacet works well on graminaceous and some dicotyledonous weeds, particularly E. crus-galli in rice fields. In China, mefenacet has been registered in transplanting or direct seeding paddy fields, either formulated as a single agent or in the form of compounding with other herbicides. Resistance to mefenacet evolves relatively slowly and mefenacet-resistance had previously not been identified in E. crus-galli.
Herbicide resistance mechanisms are classified as either target-site resistance (TSR) or non-target-site resistance (NTSR) based on the herbicide's molecular interactions. TSR mechanisms mainly occur through mutation of the target protein or increasing target protein abundance by over-expression or gene duplication, respectively. NTSR mechanisms involve preventing the herbicide from reaching its target. This is usually accomplished through either herbicide metabolic breakdown or physiological processes that impede localization of herbicide with its target or increasing transport of herbicide molecules away from the target protein. While HRAC Group 15 herbicides have a shared mode of action, recognized as inhibiting the synthesis of VLCFAs, the exact target protein(s) of these herbicides remains unclear. While VLCFAs constitute only a fraction of the total fatty acids in most plant cells, they are imperative for survival. Defined as any fatty acid with an acyl chain of 18 or more carbons, VLCFAs are involved in diverse metabolic pathways, including but not limited to the production of sphingolipids, cuticular waxes, pollen coat, and suberin. VLCFAs are also essential for cell plate formation during cytokinesis. Unlike the plastid-localized de novo synthesis of most fatty acids, VLCFAs are synthesized by endoplasmic reticulum membrane-embedded enzymes in a four-step cycle. The most important enzymes, which catalyze the first, rate-limiting step of the elongation cycle, are named VLCFA elongases (VLCFAEs). The VLCFAE mechanism involves the condensation of an acyl-CoA primer (over 16 carbons in length) with malonyl-CoA, extending the fatty acid by 2 carbons per cycle. VLCFAEs are assumed to be the primary targets of Group 15 herbicides. In angiosperm species, VLCFAEs exist in a gene family with 20–30 members.While each VLCFAE can have its own substrate preference for the elongase activity, there is also some overlap and functional redundancy. Seven VLCFAEs from Arabidopsis were successfully expressed in Saccharomyces cerevisiae and their activity affected by some Group 15 herbicides was characterized. Results revealed a surprising variety, for example: one VLCFAE was susceptible to multiple herbicides and one herbicide could inhibit multiple VLCFAEs. The combination of VLCFAE substrate promiscuity, large gene family size, and diverse herbicide effectiveness between VLCFAE paralogs can explain why, despite 50 years of use, resistance to Group 15 herbicides has evolved relatively slowly, with no TSR mechanism yet reported.
Herbicide Mefenacet control object
mefenacet this product is mainly used for transplanting rice fields. It can effectively control grass weeds and has special effects on barnyard grass. Barnyard grass can be killed before it occurs to the 3-leaf stage.
Acute toxicity herbicide Mefenacet
Effect on birds: low toxicity to birds, acute LD50 for Bobwhite quail is 5000 a.i.mg/kg. Effect on fish: moderate toxicity to fish, acute 96 hour LC50 for Salmonidae is 6 a.i.mg/L. Effect on aquatic invertebrates: moderate toxicity to aquatic invertebrates, acute 48 hour EC50 for Daphnia magna is 1.81 a.i.mg/L. Effect on algae: moderate toxicity to algae, acute 72 hour EC50 for Scenedemus subspicatus is 0.18 a.i.mg/L. Effect on earthworms: moderate toxicity to earthworms, acute 14 day LC50 for Eisenia foetida is 1000 a.i.mg/kg.
1) Acute oral LD50 for rat: >5000 a.i.mg/kg.
2) Acute dermal LD50 for rat: >5000 a.i.mg/kg.
3) Inhalation LC50 (4 h) for rat: 0.02 a.i.mg/L.
4) Skin irritant (rabbits).
5) Irritant to eyes (rabbits).
6) A skin sensitiser (guinea pigs).
Herbicide Mefenacet environmental impact
Mefenacet's production may result in its release to the environment through various waste streams; its use as a herbicide will result in its direct release to the environment. If released to air, an estimated vapor pressure of 6.4×10-4 mPa at 25 deg C indicates Mefenacet is low volatility. If released to soil, Mefenacet is expected to have Slightly mobility based upon an estimated Koc of 2964. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 4.77×10-5 Pa m3/mol. Biodegradation half-lives of 35 days using aerobic soils suggest that Mefenacet is Moderately persistent in soil. If released into water, Mefenacet is expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. An estimated BCF of 29 suggests the potential for bioconcentration in aquatic organisms is low. Mefenacet hydrolysis is stable at pH 4 to pH 9.
Herbicide Mefenacet Precautions
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Do not breathe dust/fume/gas/mist/vapors/spray.
Avoid release to the environment.
Use personal protective equipment as required.
IF exposed or concerned: Get medical advice/attention.
Get medical advice/attention if you feel unwell.
Collect spillage.
Store locked up.